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Nifedipine Tablets: Managing Blood Pressure and Heart Conditions
Nifedipine Tablets: Managing Blood Pressure and Heart Conditions
Nifedipine Tablets: Managing Blood Pressure and Heart Conditions
Nifedipine Tablets: Managing Blood Pressure and Heart Conditions
Nifedipine Tablets: Managing Blood Pressure and Heart Conditions
Nifedipine Tablets: Managing Blood Pressure and Heart Conditions
Nifedipine Tablets: Managing Blood Pressure and Heart Conditions

Nifedipine Tablets: Managing Blood Pressure and Heart Conditions

更新時(shí)間：2025-06-20

價(jià)格：  元/個(gè)
地區： 上海市
是否提供樣品： 是
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產(chǎn)品詳情
產(chǎn)品關(guān)鍵詞： Nifedipine Tablets,Calcium Channel Blocker,Angina Relief,Cardiovascular Medication
是否為生產(chǎn)商： 是
產(chǎn)品包裝規格： 10mg/table 10*10tables/box
主要銷(xiāo)售市場(chǎng)： 中國,北美洲,中/南美洲,西歐,東歐,大洋洲,亞洲,中東,非洲
產(chǎn)品描述：
PRODUCT NAME:Nifedipine Tablets
STRENGTH:10mg/table
PACKING DETAILS:10*10tables/box
STORAGE:Store in a cool and dry place below 25oC, protected from light.
SHELF LIFE:24 months
REGISTRATION DOSSIERS ARE AVAILABLE.
CONSIGNMENT MANUFACTURING, BRAND OEM/ODM SERVICE IS AVAILABLE.




Mechanism of Action

Nifedipine is a calcium channel blocker belonging to the dihydropyridine subclass. It exerts its therapeutic effects by inhibiting voltage-gated L-type calcium channels in vascular smooth muscle and myocardial cells. This blockage prevents the entry of calcium ions into cells during depolarization, reducing peripheral arterial vascular resistance and dilating coronary arteries. As a result, it reduces systemic blood pressure and increases myocardial oxygen delivery.

Uses

Nifedipine tablets are primarily used for:

  • Chronic stable angina: Reduces the frequency of angina attacks and increases exercise tolerance.
  • Vasospastic angina: Effective in preventing coronary artery spasms.
  • Hypertension: Used as monotherapy or in combination with other antihypertensive agents.
  • Off-label uses: Including Raynaud's phenomenon, severe hypertension during pregnancy, high altitude pulmonary edema, and pulmonary arterial hypertension.

Dosage and Administration

Chronic Stable Angina:

  • Immediate-release: 10 to 20 mg three times daily; maximum dose of 180 mg per day.
  • Extended-release: 30 or 60 mg daily; maximum dose of 120 mg per day.
  • Vasospastic Angina:
  • Extended-release: 30 or 60 mg daily; maximum dose of 120 mg per day.
  • Hypertension:
  • Extended-release: 30 or 60 mg daily; maximum dose of 120 mg per day.
  • Hypertensive Emergency During Pregnancy or Postpartum Period:
  • Immediate-release: 10 mg; may repeat with a 20 mg dose in 20 minutes.
  • Administration:
  • Nifedipine is available in both immediate and extended-release formulations. Immediate-release formulations can be taken without regard to meals, while some extended-release preparations require ingestion on an empty stomach.

Storage

Nifedipine tablets should be stored at room temperature, typically between 15°C and 30°C (59°F to 86°F), and protected from light.

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