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Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections
Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections
Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections
Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections
Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections
Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections
Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections

Ceftriaxone Sodium: Broad - Spectrum Antibiotic for Severe Infections

更新時(shí)間:2025-06-18

價(jià)格:  元/個(gè)
CAS號: 73384-59-5
藥典: 企業(yè)標準
級別: Pharmaceutical grade
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產(chǎn)品詳情
產(chǎn)品關(guān)鍵詞: Ceftriaxone Sodium,Third - Generation Cephalosporin,Broad - Spectrum Antibiotic,Bacterial Infections Treatment,Intravenous and Intramuscular Administration
是否為生產(chǎn)商:
產(chǎn)品包裝規格: 0.25g/Ampoule 10Ampoules/box
主要銷(xiāo)售市場(chǎng): 中國,北美洲,中/南美洲,西歐,東歐,大洋洲,亞洲,中東,非洲
是否提供樣品:
產(chǎn)品描述:
PRODUCT NAME:Ceftriaxone Sodium
STRENGTH:0.25g/Ampoule
PACKING DETAILS:10Ampoules/box
STORAGE:Store in a cool and dry place below 25oC, protected from light.
SHELF LIFE:24 months
REGISTRATION DOSSIERS ARE AVAILABLE.
CONSIGNMENT MANUFACTURING, BRAND OEM/ODM SERVICE IS AVAILABLE.




Mechanism of Action

Ceftriaxone sodium is a third-generation cephalosporin antibiotic that exerts its bactericidal effect by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), which are essential enzymes involved in the final stages of cell wall assembly. By disrupting the cross-linking of peptidoglycan chains, ceftriaxone weakens the bacterial cell wall, leading to cell lysis and death.

Uses

Ceftriaxone sodium injection is indicated for the treatment of a wide range of bacterial infections, including:

  • Respiratory tract infections (e.g., pneumonia, bronchitis)
  • Urinary tract infections (e.g., cystitis, pyelonephritis)
  • Gastrointestinal infections (e.g., enteritis, peritonitis)
  • Skin and soft tissue infections (e.g., cellulitis, abscesses)
  • Bacterial meningitis
  • Septicemia (bloodstream infections)
  • Bone and joint infections
  • Gonorrhea.

Dosage and Administration

Adults:

  • The usual daily dose is 1 to 2 grams, given once daily or in divided doses every 12 hours. The total daily dose should not exceed 4 grams.
  • For preoperative use (surgical prophylaxis), a single dose of 1 gram administered intravenously ? to 2 hours before surgery is recommended.
  • Children:
  • For children, the dosage is typically 50 to 75 mg/kg/day, divided into doses every 12 hours. For meningitis, the recommended dose is 100 mg/kg/day, divided into doses every 12 hours.
  • Neonates:
  • In neonates, the dose is usually 20 to 50 mg/kg/day, divided into doses every 12 hours.
  • Administration:
  • Ceftriaxone can be administered intravenously or intramuscularly. For intravenous administration, it should be infused over a period of 30 minutes. When administering to neonates, a 60-minute infusion is recommended to reduce the risk of bilirubin encephalopathy.
  • Important Notes:
  • Ceftriaxone should not be mixed with calcium-containing solutions due to the risk of precipitation and potential for severe adverse effects, such as bilirubin encephalopathy in neonates.
  • No dosage adjustment is necessary for patients with renal or hepatic impairment.

Storage

Ceftriaxone sodium injection should be stored at room temperature, typically between 15°C and 30°C (59°F to 86°F). It should be protected from freezing and kept in a dry place.

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